RECENT DEVELOPMENT IN THE PHYTOCHEMICAL BASED NANO DRUG DELIVERY SYSTEM FOR WOUND HEALING AND SKIN REGENERATION

*Ashirwad Sawale, Paras Raut, Shivani Kale and Aman Upaganlawar

Effective and rapid wound healing requires advanced therapeutic strategies capable of maintaining a moist wound environment, minimizing infection, and promoting tissue regeneration. Among emerging technologies, phytoconstituent-based nanodrug delivery systems have demonstrated promising potential in enhancing wound healing. These nanoscale formulations offer targeted and sustained release of bioactive compounds, enabling accelerated tissue repair while minimizing adverse effects. Nanomedicine provides a more focused and efficient therapeutic approach, addressing the limitations of conventional dosage forms by improving sitespecific delivery and bioavailability of therapeutic agents. Recent research has highlighted various nanocarrier systems such as dendrimers, hydrogels, liposomes, micelles, nanoparticles, and nanosomes that significantly enhance wound healing outcomes. These nanotechnologies not only improve the clinical relevance of treatment strategies but also offer superior therapeutic benefits, particularly in managing chronic and diabetic wounds. This review summarizes recent advancements in nanomedicine and emphasizes its expanding role in modern wound care through innovative drug delivery platforms tailored for improved healing efficacy.